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People struggling with infertility take very different views on the medical evidence around treatment and need personally tailored support from doctors to make informed choices, according to a study by Queen Mary University of London published in Sociology of Health and Illness this month.

Over 50, verapamil hcl extended release tablets 000 people have fertility treatment every year in the UK, and an estimated 70% of these use controversial “add-ons” that promise to increase their chances of having a baby but aren’t supported by solid evidence. Most fertility treatment in the UK is paid for privately, at prices from £3-5,000 for a standard IVF cycle to more than £20,000 with certain add-ons, so it’s vital that patients can make decisions based on medical evidence rather than healthcare marketing.

Private fertility care providers are often accused of manipulating vulnerable patients for financial gain, and a BBC Panorama film in 2016 investigated IVF clinics selling unproven or risky add-ons. However, research led by Queen Mary’s School of Business and Management tells a different story: While some patients prefer to delegate decisions to their doctors, others actively assess add-ons and decide to take risks, especially when fertility treatment has not worked in the past.

Researchers held in-depth interviews with 51 fertility treatment patients across England aged 29 to 47, including those personally going through IVF as well as their partners. The results show that patients share a general understanding of what counts as medical evidence but take different views of what is “good” or “enough” depending on their personal experience of infertility and IVF.

The study found that patients were expected to make their own choices about what add-ons to have—and some did want to critically assess the evidence available, but around half preferred to leave decision-making with healthcare professionals and just follow their advice. Interviews also revealed that patients looked at evidence in relation to their own experience, calculating risks and making choices based on what they had been through in the past or how many chances they felt they would have to try for a baby in the future.

Study author Dr. Josie Hamper, post-doctoral researcher at Queen Mary University of London, explained, “Our research challenges the view of IVF patients as willing to uncritically accept or request unproven and expensive treatment as a desperate act to increase their chances of having a baby; on the contrary, we found they actively make complex decisions in the intense and uncertain world of reproductive medicine.”

“Patients choosing to pay for private treatment and pursue controversial add-ons is not due to a lack of information or understanding, but personally weighing the scientific evidence up against their own unique fertility journey.”

In light of the new study, researchers are calling for healthcare professionals to rethink what “informed choice” means in a privatized system. Patients need quality information in an accessible format so they can make treatment choices themselves, but alternative strategies should also be explored to defend those who take calculated risks or defer to their doctors.

With the UK fertility regulator (HFEA) currently considering whether to fine providers for mis-selling add-ons, and the Competition and Markets Authority currently reviewing fertility clinics’ compliance with consumer law guidance, this new research provides timely evidence to inform these important discussions on the privatization of healthcare and how patients can be supported to make informed choices in the resulting market.

Study author Dr. Manuela Perrotta, reader in technology and organization at Queen Mary University of London, concluded, “Discussion around IVF add-ons often tells a story of rapacious private clinics selling useless fertility treatments to gullible patients, which is only one side of a complex story that our research works to unpick.”

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